Immunoexpression of mutant p53 and human papillomavirus related E6 oncoprotein in anal malignancies.

Article

Immunoexpression of mutant p53 and human papillomavirus related E6 oncoprotein in anal malignancies.

Indian journal of experimental biology - 1 Sept 1998

Gupta S, Sharma B K

Abstract excerpt

Immunohistochemical expression of mutant p53 protein and human papillomavirus (HPV) 16 and 18 related E6 oncoprotein was studied in 36 biopsy proved anal cancers. Mutant p53 was detected in 61.1% cases. HPV 16 and 18 E6 protein was expressed in 22.2% cases, all of which were squamous cell carcino...

Topics

Adult
Aged
Anus Neoplasms
DNA-Binding Proteins
Female
Humans
Immunohistochemistry
Male
Middle Aged
Mutation
Oncogene Proteins, Viral
Papillomaviridae
Repressor Proteins
Tumor Suppressor Protein p53

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