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Article

Morphogenesis beyond cytokinetic arrest in Saccharomyces cerevisiae.

The Journal of cell biology - 14 Dec 1998

Jiménez J, Cid V J, Cenamor R, Yuste M, Molero G, Nombela C, Sánchez M

Abstract excerpt

The budding yeast lyt1 mutation causes cell lysis. We report here that lyt1 is an allele of cdc15, a gene which encodes a protein kinase that functions late in the cell cycle. Neither cdc15-1 nor cdc15-lyt1 strains are able to septate at 37 degreesC, even though they may manage to rebud. Cells lyse after a shmoo-like projection appears at the distal pole of the daughter cell. Actin polarizes towards the distal...

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Identifiers

PMID: 9852155
DOI: 10.1083/jcb.143.6.1617
PMCID: PMC2132980

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