Article
The Clp1p/Flp1p phosphatase ensures completion of cytokinesis in response to minor perturbation of the cell division machinery in Schizosaccharomyces pombe.
Journal of cell science - 1 Aug 2004
Mishra Mithilesh, Karagiannis Jim, Trautmann Susanne, Wang Hongyan, McCollum Dannel, Balasubramanian Mohan K
Abstract excerpt
Fission yeast mutants defective in actomyosin ring formation and function exhibit a prolonged G2 delay following cytokinesis failure. This G2 delay depends on the SIN, a signaling network essential for cytokinesis, and the non-essential Cdc14p family phosphatase, Clp1p/Flp1p and has been proposed to signify a cytokinesis checkpoint mechanism. However, the physiological relevance of this proposed...
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