The SLT2 (MPK1) MAP kinase homolog is involved in polarized cell growth in Saccharomyces cerevisiae.

doi:10.1083/jcb.123.6.1821

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Article

The SLT2 (MPK1) MAP kinase homolog is involved in polarized cell growth in Saccharomyces cerevisiae.

The Journal of cell biology - 1 Dec 1993

Mazzoni C, Zarov P, Rambourg A, Mann C

Abstract excerpt

Bud emergence, spindle pole body duplication and DNA replication are all dependent on the activation of the CDC28 protein kinase at the Start point in the G1 phase of the cell cycle. Bud emergence requires polarization of the cytoskeleton and secretory vesicles to a specific site on the cell surface. Cdc28p activated by G1-cyclins triggers polarization of actin to the site of bud emergence and favors apical bud...

Topics

Actins
Amino Acid Sequence
Animals
Biological Evolution
CDC28 Protein Kinase, S cerevisiae
Calcium-Calmodulin-Dependent Protein Kinases
Cloning, Molecular
Conserved Sequence
Cytoskeleton
Fungal Proteins
Genes, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Lethal

Genotype

Microscopy, Electron

Mitogen-Activated Protein Kinases

Molecular Sequence Data

Mutagenesis

Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 8276900
DOI: 10.1083/jcb.123.6.1821
PMCID: PMC2290862

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8276900-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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