Article
Identification of alpha-dystroglycan as a receptor for lymphocytic choriomeningitis virus and Lassa fever virus.
Science (New York, N.Y.) - 11 Dec 1998
Cao W, Henry M D, Borrow P, Yamada H, Elder J H, Ravkov E V, Nichol S T, Compans R W, Campbell K P, Oldstone M B
Abstract excerpt
A peripheral membrane protein that is interactive with lymphocytic choriomeningitis virus (LCMV) was purified from cells permissive to infection. Tryptic peptides from this protein were determined to be alpha-dystroglycan (alpha-DG). Several strains of LCMV and other arenaviruses, including Lassa...
Topics
- Amino Acid Sequence
- Animals
- Arenavirus
- Cell Line
- Cytoskeletal Proteins
- Dystroglycans
- Lassa virus
- Lymphocytic choriomeningitis virus
- Membrane Glycoproteins
- Mice
- Molecular Sequence Data
- Mutation
- Receptors, Virus
- Recombinant Fusion Proteins
- Virus Replication