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Article

Old world arenaviruses enter the host cell via the multivesicular body and depend on the endosomal sorting complex required for transport.

PLoS pathogens - 1 Sept 2011

Pasqual Giulia, Rojek Jillian M, Masin Mark, Chatton Jean-Yves, Kunz Stefan

Abstract excerpt

The highly pathogenic Old World arenavirus Lassa virus (LASV) and the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) use α-dystroglycan as a cellular receptor and enter the host cell by an unusual endocytotic pathway independent of clathrin, caveolin, dynamin, and actin. Upon internalization, the viruses are delivered to acidified endosomes in a Rab5-independent manner bypassing classical routes...

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Identifiers

PMID: 21931550
DOI: 10.1371/journal.ppat.1002232
PMCID: PMC3169553

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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