Mutations in nonconserved domains of Ty3 integrase affect multiple stages of the Ty3 life cycle.

doi:10.1128/JVI.73.1.453-465.1999

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Article

Mutations in nonconserved domains of Ty3 integrase affect multiple stages of the Ty3 life cycle.

Journal of virology - 1 Jan 1999

Nymark-McMahon M H, Sandmeyer S B

Abstract excerpt

Ty3, a retroviruslike element of Saccharomyces cerevisiae, transposes into positions immediately upstream of RNA polymerase III-transcribed genes. The Ty3 integrase (IN) protein is required for integration of the replicated, extrachromosomal Ty3 DNA. In retroviral IN, a conserved core region is s...

Topics

Amino Acid Sequence
Base Sequence
DNA Replication
Integrases
Molecular Sequence Data
Mutation
RNA-Directed DNA Polymerase
Retroelements
Saccharomyces cerevisiae
Structure-Activity Relationship

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