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Article

Ty3 integrase mutants defective in reverse transcription or 3'-end processing of extrachromosomal Ty3 DNA.

Journal of virology - 1 Jul 1996

Kirchner J, Sandmeyer S B

Abstract excerpt

Ty3, a retroviruslike element in Saccharomyces cerevisiae, encodes an integrase (IN) which is essential for position-specific transposition. The Ty3 integrase contains the highly conserved His-Xaa(3-7)-His-Xaa(23-32)-Cys-Xaa(2)-Cys and Asp, Asp-Xaa(35)-Glu [D,D(35)E] motifs found in retroviral integrases. Mutations were introduced into the coding region for the Ty3 integrase to determine the effects in vivo of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 8676501
DOI: 10.1128/JVI.70.7.4737-4747.1996
PMCID: PMC190411

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Ty3 integrase mutants defective in reverse transcription or 3'-end processing of extrachromosomal Ty3 DNA.PMID 8676501Read ↗

Mutations in nonconserved domains of Ty3 integrase affect multiple stages of the Ty3 life cycle.Semantic proximity Read ↗

Ty3 integrase is required for initiation of reverse transcription.Semantic proximity Read ↗

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A truncation mutant of the 95-kilodalton subunit of transcription factor IIIC reveals asymmetry in Ty3 integration.Semantic proximity Read ↗

Mutations in the Ty3 major homology region affect multiple steps in Ty3 retrotransposition.Semantic proximity Read ↗

Characterization of a transpositionally active Ty3 element and identification of the Ty3 integrase protein.Semantic proximity Read ↗

Host factors that affect Ty3 retrotransposition in Saccharomyces cerevisiae.Semantic proximity Read ↗

Transfer RNA genes are genomic targets for de Novo transposition of the yeast retrotransposon Ty3.Semantic proximity Read ↗

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Localization of sequences required in cis for yeast Ty1 element transposition near the long terminal repeats: analysis of mini-Ty1 elements.Semantic proximity Read ↗

The yeast retrotransposons Ty1 and Ty3 require the RNA Lariat debranching enzyme, Dbr1p, for efficient accumulation of reverse transcripts.Semantic proximity Read ↗

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