Article
Physical and genetic interactions between Alx4 and Cart1.
Development (Cambridge, England) - 1 Jan 1999
Qu S, Tucker S C, Zhao Q, deCrombrugghe B, Wisdom R
Abstract excerpt
Alx4 and Cart1 are closely related members of the family of transcription factors that contain the paired-type homeodomain. In contrast to other types of homeodomains, the paired-type homeodomain has been shown to mediate high-affinity sequence-specific DNA binding to palindromic elements as eith...
Topics
- Animals
- Cartilage
- Craniofacial Abnormalities
- DNA-Binding Proteins
- Dimerization
- Gene Dosage
- Gene Expression Regulation, Developmental
- Gene Targeting
- Hedgehog Proteins
- Homeodomain Proteins
- In Situ Hybridization
- Mice
- Mice, Inbred Strains
- Mutation
- Neoplasm Proteins
- Nuclear Proteins
- Phenotype
- Polydactyly
