Article
Effect of ovariectomy in heart failure-prone SHHF/Mcc-facp rats.
The American journal of physiology - 1 Dec 1998
Sharkey L C, Holycross B J, Park S, McCune S A, Hoversland R, Radin M J
Abstract excerpt
The importance of the loss of ovarian function to the progression of hypertension and heart disease in women is controversial. We investigated whether ovariectomy would accelerate development of hypertension, congestive heart failure, and neurohumoral activation in adult spontaneous hypertension...
Topics
- Animals
- Blood Pressure
- Cardiac Output, Low
- Disease Progression
- Female
- Genetic Predisposition to Disease
- Hypertension
- Myocardium
- Myosins
- Organ Size
- Ovariectomy
- Rats
- Rats, Inbred Strains
- Reference Values
- Survival Analysis
- Ventricular Function, Left