Article
Plasma TAFI levels influence the clot lysis time in healthy individuals in the presence of an intact intrinsic pathway of coagulation.
Thrombosis and haemostasis - 1 Nov 1998
Mosnier L O, von dem Borne P A, Meijers J C, Bouma B N
Abstract excerpt
Thrombin Activatable Fibrinolysis Inhibitor (TAFI) is a recently identified fibrinolysis inhibitor in plasma, that when converted to an enzyme potently attenuates fibrinolysis. It is activated by relatively high concentrations of thrombin that exceed the thrombin concentration required for fibrin...
Topics
- Blood Coagulation
- Carboxypeptidase B2
- Carboxypeptidases
- Colorimetry
- Dose-Response Relationship, Drug
- Enzyme Activation
- Enzyme-Linked Immunosorbent Assay
- Factor XI
- Fibrinolysis
- Genetic Variation
- Humans
- Nephelometry and Turbidimetry
- Reference Values
- Thrombin
- Thrombomodulin
- Time Factors