Article
Infection with dual-tropic human immunodeficiency virus type 1 variants associated with rapid total T cell decline and disease progression in injection drug users.
The Journal of infectious diseases - 1 Aug 1998
Yu X F, Wang Z, Vlahov D, Markham R B, Farzadegan H, Margolick J B
Abstract excerpt
The characteristics of sequential human immunodeficiency virus type 1 (HIV-1) isolates from 12 seroconverters among injection drug users selected for either rapid or slow disease progression were evaluated. All 6 patients who developed AIDS within 5 years were initially infected with syncytium-in...
Topics
- Adult
- Amino Acid Sequence
- CD4 Lymphocyte Count
- CD4-Positive T-Lymphocytes
- CD8-Positive T-Lymphocytes
- Cell Line
- Cells, Cultured
- Disease Progression
- Female
- Genetic Variation
- HIV Envelope Protein gp120
- HIV Seropositivity
- HIV-1
- Humans
- Male
- Molecular Sequence Data
- Peptide Fragments
- Sequence Homology, Amino Acid