Article
Human immunodeficiency virus type 1 vpr protein transactivation function: mechanism and identification of domains involved.
Journal of molecular biology - 11 Dec 1998
Forget J, Yao X J, Mercier J, Cohen E A
Abstract excerpt
The human immunodeficiency virus type 1 (HIV-1) Vpr protein is a virion-associated protein that localizes in the nucleus of infected cells. Vpr has been shown to facilitate HIV infection of non-dividing cells such as macrophages by contributing to the nuclear translocation of the pre-integration...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Chloramphenicol O-Acetyltransferase
- DNA Primers
- DNA, Viral
- G2 Phase
- Gene Products, vpr
- Genes, Reporter
- Genes, Viral
- HIV Long Terminal Repeat
- HIV-1
- Humans
- Jurkat Cells
- Leukemia Virus, Murine
- Mice
- Molecular Sequence Data
- Mutation