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Article

Adenovirus-Mediated Gene Transfer to Nucleus Pulposus Cells

1 Nov 1998

Abstract excerpt

STUDY DESIGN: In vitro and in vivo studies using a rabbit model were performed to determine the feasibility of adenovirus-mediated gene transfer to the intervertebral disc. OBJECTIVES: This study was conducted to determine whether it is possible to transfer genes to cells within the intervertebral disc by direct injection of an adenovirus and to determine the duration of gene expression obtained by this method....

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Identifiers

PMID: 9836359
DOI: 10.1097/00007632-199811150-00016

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