Menisci are Efficiently Transduced by Recombinant Adeno-Associated virus Vectors in Vitro and in Vivo

Abstract excerpt

BACKGROUND: Meniscal tears remain an unsolved problem in sports medicine. Gene transfer is a potential approach to enhancing meniscal repair. Recombinant adeno-associated virus is a method of gene transfer that has advantages over previously used approaches to this problem. HYPOTHESIS: Direct gene transfer to meniscal cells can be accomplished using recombinant adeno-associated virus in vitro and in vivo. STUDY...

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