Article
Ethylene oxide-protein adduct formation in humans: influence of glutathione-S-transferase polymorphisms.
International archives of occupational and environmental health - 1 Oct 1998
Müller M, Krämer A, Angerer J, Hallier E
Abstract excerpt
OBJECTIVE: The influence of the polymorphic human glutathione-S-transferase (GST) T1 and M1 genotypes (classified as "conjugators" and "nonconjugators") on the biological effects of nonoccupational ethylene oxide exposure as reflected by the formation of globin N2-hydroxyethylvaline adducts was investigated. Specific attention was paid to smoking as a potential source of exposure. A total of 27 Caucasian...
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