Article
Ethylene oxide-protein adduct formation in humans: influence of glutathione-S-transferase polymorphisms.
International archives of occupational and environmental health - 1 Oct 1998
Müller M, Krämer A, Angerer J, Hallier E
Abstract excerpt
OBJECTIVE: The influence of the polymorphic human glutathione-S-transferase (GST) T1 and M1 genotypes (classified as "conjugators" and "nonconjugators") on the biological effects of nonoccupational ethylene oxide exposure as reflected by the formation of globin N2-hydroxyethylvaline adducts was i...
Topics
- Case-Control Studies
- DNA Adducts
- Environmental Exposure
- Ethylene Oxide
- Female
- Genotype
- Glutathione Transferase
- Humans
- Male
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Smoking
- Statistics, Nonparametric
- Substrate Specificity
- Surveys and Questionnaires
- Valine