Article
Apoptosis in mouse embryos: elevated levels in pregastrulae and in the distal anterior region of gastrulae of normal and mutant mice.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Nov 1998
Manova K, Tomihara-Newberger C, Wang S, Godelman A, Kalantry S, Witty-Blease K, De Leon V, Chen W S, Lacy E, Bachvarova R F
Abstract excerpt
The pattern of apoptotic cell death has been surveyed in prestreak and primitive streak embryos of four strains of mice and in three mutants affecting gastrulation. In C57BL/6 embryos, a high level of cell death occurs in the early egg cylinder stage at embryonic day 5 (E5) to E5.5. In all strain...
Topics
- Animals
- Apoptosis
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
- Cell Division
- DNA-Binding Proteins
- Embryonic and Fetal Development
- Female
- Gastrula
- Gene Expression Regulation, Developmental
- Growth Substances
- Hepatocyte Nuclear Factor 4
- In Situ Nick-End Labeling