Article
Apoptosis in the lens anlage of the heritable lens aplastic mouse (lap mouse).
Teratology - 1 Aug 1998
Aso S, Tashiro M, Baba R, Sawaki M, Noda S, Fujita M
Abstract excerpt
Adult homozygous lap mice show various eye abnormalities, such as aphakia, retinal disorganization, and dysplasia of the cornea and anterior chamber. In the fetal eye of a homozygous lap mouse, the lens placode seems to develop normally. However, the lens vesicle progresses abnormally to form a mass of cells without a cavity, and the mass vanishes soon afterward. We examined cell death in the lens anlage of this...
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