Article
Apoptosis in the lens anlage of the heritable lens aplastic mouse (lap mouse).
Teratology - 1 Aug 1998
Aso S, Tashiro M, Baba R, Sawaki M, Noda S, Fujita M
Abstract excerpt
Adult homozygous lap mice show various eye abnormalities, such as aphakia, retinal disorganization, and dysplasia of the cornea and anterior chamber. In the fetal eye of a homozygous lap mouse, the lens placode seems to develop normally. However, the lens vesicle progresses abnormally to form a m...
Topics
- Animals
- Aphakia
- Apoptosis
- Bromodeoxyuridine
- Eye
- Eye Abnormalities
- Female
- Gestational Age
- Homozygote
- Immunohistochemistry
- Lens, Crystalline
- Male
- Mice
- Mice, Inbred BALB C
- Mice, Mutant Strains
- Microscopy, Electron
- Mutation
- Pregnancy