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Article

Increased incidence of apoptosis in transforming growth factor alpha-deficient mouse blastocysts.

Biology of reproduction - 1 Jul 1998

Brison D R, Schultz R M

Abstract excerpt

We previously demonstrated that exogenous transforming growth factor alpha (TGFalpha) reduces the incidence of apoptosis in mouse blastocysts that develop in vitro but does not result in an increase in cell number or the incidence of development to the blastocyst stage. Thus, TGFalpha may function as a cell survival factor in the preimplantation mouse embryo. To extend these studies, we have now examined the...

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PMID: 9675004
DOI: 10.1095/biolreprod59.1.136

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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