Increased incidence of apoptosis in transforming growth factor alpha-deficient mouse blastocysts.

doi:10.1095/biolreprod59.1.136

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Article

Increased incidence of apoptosis in transforming growth factor alpha-deficient mouse blastocysts.

Biology of reproduction - 1 Jul 1998

Brison D R, Schultz R M

Abstract excerpt

We previously demonstrated that exogenous transforming growth factor alpha (TGFalpha) reduces the incidence of apoptosis in mouse blastocysts that develop in vitro but does not result in an increase in cell number or the incidence of development to the blastocyst stage. Thus, TGFalpha may functio...

Topics

Animals
Apoptosis
Blastocyst
Cell Division
Cell Nucleus
Cell Survival
Culture Techniques
Female
Fertility
Image Processing, Computer-Assisted
Male
Mice
Mice, Mutant Strains
Microscopy, Confocal
Phenotype
Transforming Growth Factor alpha

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