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Granulocyte colony-stimulating factor activates a 72-kDa isoform of STAT3 in human neutrophils

1 Nov 1998

Abstract excerpt

Granulocyte colony-stimulating factor (G-CSF) signaling involves activation of STATs, proteins that serve the dual function of signal transduction and activation of transcription. We previously demonstrated that G-CSF activated a distinct Stat3-like protein in immature and mature normal myeloid cells, StatG. StatG in normal immature human myeloid cells, i.e. adult CD34+ bone marrow cells, was composed of...

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PMID: 9823774
DOI: 10.1002/jlb.64.5.675

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