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Article

Lack of association of CYP1 B1*3 polymorphism and ovarian cancer in a Caucasian population.

The International journal of biological markers - 1 Jan 2000

Cecchin E, Russo A, Campagnutta E, Martella L, Toffoli G

Abstract excerpt

CYP1B1 is the enzyme with the highest efficiency of conversion of estradiol to 4-hydroxyestradiol in humans. This metabolite has a well-known carcinogenic effect interacting with genomic DNA and has been hypothesized to be partly responsible for the role played by estrogens in ovarian cancer development. A polymorphism has been described for this enzyme causing a Leu to Val substitution in position 432...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15255550
DOI: 10.1177/172460080401900212

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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