Article
In vivo analysis of the Hsp90 cochaperone Sti1 (p60).
Molecular and cellular biology - 1 Jan 1997
Chang H C, Nathan D F, Lindquist S
Abstract excerpt
Hsp90 interacts with Sti1 (p60) in lysates of yeast and vertebrate cells. Here we provide the first analysis of their interaction in vivo. Saccharomyces cerevisiae mutations that eliminate Sti1 or reduce intracellular concentrations of Hsp90 individually have little or no effect on growth at norm...
Topics
- Amino Acid Isomerases
- Carrier Proteins
- Peptidyl-Prolyl Isomerase F
- Cyclophilins
- Fungal Proteins
- Genes, Fungal
- Genes, Lethal
- HSP40 Heat-Shock Proteins
- HSP70 Heat-Shock Proteins
- HSP90 Heat-Shock Proteins
- Heat-Shock Proteins
- Molecular Chaperones
- Mutation
- Oncogene Protein pp60(v-src)
- Peptidylprolyl Isomerase
- Phosphorylation
- Point Mutation
- Proto-Oncogene Proteins pp60(c-src)