Article
De novo mutations and allelic diversity at minisatellite locus D7S22 investigated by allele-specific four-state MVR-PCR analysis.
Human molecular genetics - 1 Dec 1998
Andreassen R, Olaisen B
Abstract excerpt
We have studied the allelic diversity and de novo mutations at the hypervariable minisatellite locus D7S22. A four-state minisatellite variant repeat unit mapping by PCR (MVR-PCR) method was developed for this purpose, and a substitution polymorphism close to the repeat array was used to design a...
Topics
- Alleles
- Base Sequence
- Chromosomes, Human, Pair 7
- DNA
- DNA Primers
- Female
- Forensic Medicine
- Genetic Variation
- Humans
- Male
- Microsatellite Repeats
- Mutation
- Paternity
- Polymerase Chain Reaction
- Sequence Analysis, DNA