Article
Mutation rate in the hypervariable VNTR g3 (D7S22) is affected by allele length and a flanking DNA sequence polymorphism near the repeat array.
American journal of human genetics - 1 Aug 1996
Andreassen R, Egeland T, Olaisen B
Abstract excerpt
The hypervariable human minisatellite locus D7S22 (g3) is highly polymorphic. The allelic distribution in D7S22 features a size clustering of the alleles and a comparably low allelic diversity among small alleles. This reduced diversity could reflect a situation where some alleles are less likely...
Topics
- Alleles
- Base Sequence
- DNA, Satellite
- Female
- Humans
- Male
- Minisatellite Repeats
- Models, Genetic
- Molecular Sequence Data
- Mutagenesis
- Paternity
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Sequence Analysis, DNA