Article
Four-state MVR-PCR: increased discrimination of digital DNA typing by simultaneous analysis of two polymorphic sites within minisatellite variant repeats at D1S8.
Human molecular genetics - 1 Oct 1993
Tamaki K, Monckton D G, MacLeod A, Allen M, Jeffreys A J
Abstract excerpt
Minisatellite variant repeat mapping by PCR (MVR-PCR) provides a digital approach to DNA typing that can reveal huge levels of variation at minisatellite loci. MVR-PCR has so far been applied to three human minisatellites, including the hypervariable locus D1S8. Previous analysis at D1S8 was based on the discrimination of repeat unit types that differ by a single base substitution. We now show that a second...
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