Article
Polymorphisms of the beta chain of the high-affinity immunoglobulin E receptor (Fcepsilon RI-beta) in South African black and white asthmatic and nonasthmatic individuals.
American journal of respiratory and critical care medicine - 1 Nov 1998
Green S L, Gaillard M C, Song E, Dewar J B, Halkas A
Abstract excerpt
We used amplification refractory mutation system-polymerase chain reaction (ARMS-PCR) to document the prevalence of three mutations in the beta chain of the high-affinity IgE receptor (Fcepsilon RI-beta): I181L, V183L, and E237G in a sample of black and white asthmatic and control subjects in Sou...
Topics
- Adolescent
- Adult
- Asthma
- Black People
- Chi-Square Distribution
- Child
- Exons
- Female
- Gene Frequency
- Glutamic Acid
- Glycine
- Humans
- Hypersensitivity, Immediate
- Immunoglobulin E
- Isoleucine
- Leucine
- Male
- Middle Aged