Article
Comparison of oncogene mutation detection and telomerase activity for the molecular staging of non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 1997
Ahrendt S A, Yang S C, Wu L, Westra W H, Jen J, Califano J A, Sidransky D
Abstract excerpt
Novel oncogene mutation detection techniques have demonstrated that standard histopathological examination may fail to detect clinically significant metastatic cancer cells. Recently, telomerase activity has been detected in most immortal cell lines and human tumors, potentially providing a novel...
Topics
- Adult
- Aged
- Carcinoma, Non-Small-Cell Lung
- Female
- Genes, p53
- Genes, ras
- Humans
- Lung Neoplasms
- Lymph Nodes
- Lymphatic Metastasis
- Male
- Middle Aged
- Mutation
- Neoplasm Staging
- Telomerase