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Article

Secondary structure of the 5′ nontranslated regions of hepatitis C virus and pestivirus genomic RNAs

1 Jan 1992

Abstract excerpt

The RNA genomes of human hepatitis C virus (HCV) and the animal pestiviruses responsible for bovine viral diarrhea (BVDV) and hog cholera (HChV) have relatively lengthy 5' nontranslated regions (5'NTRs) sharing short segments of conserved primary nucleotide sequence. The functions of these 5'NTRs are poorly understood. By comparative sequence analysis and thermodynamic modeling of the 5'NTRs of multiple BVDV and...

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PMID: 1329037
DOI: 10.1093/nar/20.19.5041

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