"Suicide" gene for the control of graft-versus-host disease.

doi:10.1097/00062752-199811000-00021

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Article

"Suicide" gene for the control of graft-versus-host disease.

Current opinion in hematology - 1 Nov 1998

Tiberghien P

Abstract excerpt

Specific and conditional in vivo ablation of alloreactive donor T cells after allogeneic hematopoietic stem cell transplantation could significantly contribute to preventing and treating graft-versus-host disease (GVHD). The use of donor T cells expressing a "suicide" gene such as the thymidine k...

Topics

Animals
Clinical Trials as Topic
Genetic Predisposition to Disease
Genetic Therapy
Genetic Vectors
Graft vs Host Disease
Hematopoietic Stem Cell Transplantation
Herpesvirus 1, Human
Humans
Thymidine Kinase

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