Article
Variation in the AU(AT)-rich element within the 3'-untranslated region of PPP1R3 is associated with variation in plasma glucose in aboriginal Canadians.
The Journal of clinical endocrinology and metabolism - 1 Nov 1998
Hegele R A, Harris S B, Zinman B, Wang J, Cao H, Hanley A J, Tsui L C, Scherer S W
Abstract excerpt
We are investigating associations between variations in candidate genes on chromosome 7q and diabetes-related phenotypes in Canadian Oji-Cree. One of these genes encodes the skeletal muscle regulatory G subunit of the glycogen-associated form of protein phosphatase 1 (PPPIR3), which may play a key role in muscle glycogen metabolism. There is a common 5-bp insertion-deletion polymorphism in a messenger ribonucleic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
