Article
Significance of 3'UTR and Pathogenic Haplotype in Glucose-6-Phosphate Deficiency.
Laboratory medicine - 1 Feb 2017
Chaowanathikhom Mallika, Nuchnoi Pornlada, Palasuwan Duangdao
Abstract excerpt
OBJECTIVE: To determine the polymorphisms in the 3' untranslated region (3'UTR) of the G6PD gene and analyze the specific SNPs or haplotypes that may affect messenger RNA (mRNA) secondary structure by in silico analysis. METHODS: We studied the 3'UTR polymorphisms in 107 healthy subjects living in Thailand (ethnicities unknown). The haplotype was analyzed using Haploview software. mRNA secondary structure and...
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