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Article

Genotype-specific transcriptional regulation of PAI-1 gene by insulin, hypertriglyceridemic VLDL, and Lp(a) in transfected, cultured human endothelial cells.

Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 1998

Grenett H E, Benza R L, Fless G M, Li X N, Davis G C, Booyse F M

Abstract excerpt

Plasminogen activator inhibitor-1 (PAI-1) has been shown to be an independent risk factor for coronary artery disease. Variations in plasma PAI-1 levels have been attributed to variations in the PAI-1 gene, and associations between PAI-1 levels and PAI-1 genotypes suggest that PAI-1 expression ma...

Topics

Cells, Cultured
Deoxyribonuclease HindIII
Endothelium, Vascular
Genotype
Humans
Hypertriglyceridemia
Insulin
Lipoprotein(a)
Lipoproteins, VLDL
Plasminogen Activator Inhibitor 1
Polymorphism, Restriction Fragment Length

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Homology, Nucleic Acid

Transcription, Genetic

Transfection

Umbilical Cord

Source

Identifiers

PMID: 9812921
DOI: 10.1161/01.atv.18.11.1803

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9812921-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Genotype-specific transcriptional regulation of PAI-1 gene by insulin, hypertriglyceridemic VLDL, and Lp(a) in transfected, cultured human endothelial cells.PMID 9812921Read ↗

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