No association of the plasminogen activator inhibitor-1 promoter 4G/5G polymorphism with inhibitor level during basal transcription in vitro.

doi:10.1532/ijh97.a10310

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Article

No association of the plasminogen activator inhibitor-1 promoter 4G/5G polymorphism with inhibitor level during basal transcription in vitro.

International journal of hematology - 1 May 2004

Zhan Mei, Zhou Yuling, Han Zhong Chao

Abstract excerpt

Plasminogen activator inhibitor type 1 (PAI-1) has been shown to be an independent risk factor for coronary artery disease, myocardial infarction, and cerebrovascular events. Previous studies on variations in plasma PAI-1 levels and associations between PAI-1 levels and PAI-1 genotypes have suggested that PAI-1 expression maybe regulated in a genotype-specific manner by insulin, hypertriglyceridemic very...

Topics

Cell Line, Tumor
Chloramphenicol O-Acetyltransferase
Genotype
Humans
Nuclear Proteins
Plasminogen Activator Inhibitor 1
Polymorphism, Genetic
Promoter Regions, Genetic
Protein Binding
Transcription, Genetic
Transfection

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PMID: 15218974
DOI: 10.1532/ijh97.a10310

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