Article
Congenital stationary night blindness in the dog: common mutation in the RPE65 gene indicates founder effect.
Molecular vision - 30 Oct 1998
Aguirre G D, Baldwin V, Pearce-Kelling S, Narfström K, Ray K, Acland G M
Abstract excerpt
PURPOSE: To clone and characterize the canine RPE65 cDNA from normal dog, examine for mutations, and establish if the mutation identified in Swedish briard dogs with retinal dystrophy is present in dogs of the same breed that originated from the United States and other countries, and are affected...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Carrier Proteins
- Cloning, Molecular
- Dogs
- Electroretinography
- Eye Proteins
- Founder Effect
- Molecular Sequence Data
- Mutation
- Night Blindness