Article
Optimizing outcome after unrelated marrow transplantation by comprehensive matching of HLA class I and II alleles in the donor and recipient.
Blood - 15 Nov 1998
Petersdorf E W, Gooley T A, Anasetti C, Martin P J, Smith A G, Mickelson E M, Woolfrey A E, Hansen J A
Abstract excerpt
In unrelated marrow transplantation, the benefit of matching class II HLA-DRB1 and DQB1 alleles of the donor and recipient is well documented. Little is known about the clinical relevance of matching for class I HLA-A, B, and C alleles. We used DNA-amplification methods to identify the HLA-A, B,...
Topics
- Alleles
- Bone Marrow Transplantation
- DNA
- Graft Rejection
- Graft vs Host Disease
- HLA Antigens
- Histocompatibility Testing
- Humans
- Life Tables
- Retrospective Studies
- Risk
- Sequence Analysis, DNA
- Serotyping
- Survival Analysis
- Tissue Donors