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Article

p53 and p16/CDKN2 gene mutations in esophageal tumors from a high-incidence area in South Africa.

International journal of cancer - 23 Nov 1998

Gamieldien W, Victor T C, Mugwanya D, Stepien A, Gelderblom W C, Marasas W F, Geiger D H, van Helden P D

Abstract excerpt

Squamous cell carcinoma of the esophagus has an uneven geographic distribution, with a high incidence in the Transkei region of Eastern Cape Province, South Africa. The precise molecular events associated with tumorigenesis of esophageal cancer in this region have not been characterized. DNA from human esophageal squamous cell carcinomas (n = 76), as well as adjacent tissue samples (n = 9) and blood (n = 50) from...

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Identifiers

PMID: 9808520
DOI: 10.1002/(sici)1097-0215(19981123)78:5<544::aid-ijc3>3.0.co;2-t

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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