Fertile offspring derived from mammalian eggs lacking either animal or vegetal poles.

doi:10.1242/dev.125.23.4803

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Article

Fertile offspring derived from mammalian eggs lacking either animal or vegetal poles.

Development (Cambridge, England) - 1 Dec 1998

Zernicka-Goetz M

Abstract excerpt

In all animals so far tested, removing either pole of the undivided egg prevents normal development: embryos may arrest early, lack organs, or the adults may be sterile. These experiments have shown that spatial patterning of the egg is of utmost importance for subsequent development. However, th...

Topics

Animals
Blastocyst
Body Patterning
Cell Polarity
Female
Fertility
Genotype
Male
Mammals
Mice
Mice, Inbred C57BL
Mice, Inbred CBA
Morula
Ovum
Zygote

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