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Article

Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis.

Nature - 1 Jan 2000

Surani M A, Barton S C, Norris M L

Abstract excerpt

It has been suggested that the failure of parthenogenetic mouse embryos to develop to term is primarily due to their aberrant cytoplasm and homozygosity leading to the expression of recessive lethal genes. The reported birth of homozygous gynogenetic (male pronucleus removed from egg after fertil...

Topics

Animals
Cell Nucleus
Embryo, Mammalian
Female
Fertilization
Genes
Genotype
Haploidy
Male
Mice
Mice, Inbred Strains
Ovum
Parthenogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 6709062
DOI: 10.1038/308548a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-6709062-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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