Article
Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis.
Nature - 1 Jan 2000
Surani M A, Barton S C, Norris M L
Abstract excerpt
It has been suggested that the failure of parthenogenetic mouse embryos to develop to term is primarily due to their aberrant cytoplasm and homozygosity leading to the expression of recessive lethal genes. The reported birth of homozygous gynogenetic (male pronucleus removed from egg after fertilization) mice and of animals following transplantation of nuclei from parthenogenetic embryos to enucleated fertilized...
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