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Article

The Intracellular Localization of Deoxycytidine Kinase

1 Nov 1998

Abstract excerpt

Deoxycytidine kinase (dCK) catalyzes the rate-limiting step of the deoxynucleoside salvage pathway in mammalian cells and plays a key role in the activation of several pharmacologically important nucleoside analogs. Using a highly specific polyclonal antibody raised against a C-terminal peptide of the human dCK, we analyzed its subcellular localization by Western blots of biochemically fractionated nuclear and...

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PMID: 9804782
DOI: 10.1074/jbc.273.46.30239

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