Article
ADH genotypes and alcohol use and dependence in Europeans.
Alcoholism, clinical and experimental research - 1 Oct 1998
Whitfield J B, Nightingale B N, Bucholz K K, Madden P A, Heath A C, Martin N G
Abstract excerpt
We have tested for effects of alcohol dehydrogenase (ADH) genotypes on self-reported alcohol consumption and symptoms of alcohol dependence, recorded on three occasions up to 15 years apart, in 377 male and female subjects of European descent. ADH2 genotype had significant effects on both consumption and dependence in the men, but not in the women. The effects of ADH3 genotype were considerably less than those of...
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