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Article

Gene environment interactions with a novel variable Monoamine Oxidase A transcriptional enhancer are associated with antisocial personality disorder.

Biological psychology - 1 Jul 2011

Philibert Robert A, Wernett Pamela, Plume Jeff, Packer Hans, Brody Gene H, Beach Steven R H

Abstract excerpt

Monoamine Oxidase A (MAOA) is a critical enzyme in the catabolism of monoaminergic neurotransmitters. MAOA transcriptional activity is thought to be regulated by a well characterized 30 base pair (bp) variable nucleotide repeat (VNTR) that lies approximately ∼1000 bp upstream of the transcriptional start site (TSS). However, clinical associations between this VNTR genotype and behavioral states have been...

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Source

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Identifiers

PMID: 21554924
DOI: 10.1016/j.biopsycho.2011.04.007
PMCID: PMC3134149

Genes

MAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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