Article
Clinical characterization of polymorphisms in the sulphonylurea receptor 1 gene in Japanese subjects with Type 2 diabetes mellitus.
Diabetic medicine : a journal of the British Diabetic Association - 1 Oct 1998
Ishiyama-Shigemoto S, Yamada K, Yuan X, Koyama W, Nonaka K
Abstract excerpt
To assess the association of polymorphisms at the sulphonylurea receptor (SUR1) gene with the development of Type 2 diabetes mellitus, 456 subjects, 236 with Type 2 diabetes and 220 non-diabetic controls, were analysed for variants at exon 7, exon 22 and intron 24 of the SUR1 gene by the polymera...
Topics
- ATP-Binding Cassette Transporters
- Blood Glucose
- DNA
- Diabetes Mellitus, Type 2
- Electrophoresis, Agar Gel
- Exons
- Female
- Gene Frequency
- Genetic Variation
- Genotype
- Humans
- Introns
- Japan
- Male
- Middle Aged
- Obesity
- Polymorphism, Genetic
- Potassium Channels
