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Clinical characterization of polymorphisms in the sulphonylurea receptor 1 gene in Japanese subjects with Type 2 diabetes mellitus.

Diabetic medicine : a journal of the British Diabetic Association - 1 Oct 1998

Ishiyama-Shigemoto S, Yamada K, Yuan X, Koyama W, Nonaka K

Abstract excerpt

To assess the association of polymorphisms at the sulphonylurea receptor (SUR1) gene with the development of Type 2 diabetes mellitus, 456 subjects, 236 with Type 2 diabetes and 220 non-diabetic controls, were analysed for variants at exon 7, exon 22 and intron 24 of the SUR1 gene by the polymerase chain reaction and restriction fragment length polymorphism. The T761T substitution in exon 22 of the SUR1 gene was...

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PMID: 9796882
DOI: 10.1002/(SICI)1096-9136(199810)15:10<826::AID-DIA685>3.0.CO;2-H

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Clinical characterization of polymorphisms in the sulphonylurea receptor 1 gene in Japanese subjects with Type 2 diabetes mellitus.PMID 9796882Read ↗

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Impact of sulfonylurea receptor 1 genetic variability on non-insulin-dependent diabetes mellitus prevalence and treatment: a population study.Semantic proximity Read ↗

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Impact of the sulfonylurea receptor 1 (SUR1) exon 16-3c/t polymorphism on acute hyperglycaemia in type 2 diabetic patients.Semantic proximity Read ↗

Association of sulfonylurea receptor 1 genotype with therapeutic response to gliclazide in type 2 diabetes.Semantic proximity Read ↗

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