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Article

Application of RSCA for the typing of HLA-DPB1.

Human immunology - 1 Nov 1998

Ramon D S, Argüello J R, Cox S T, McWhinnie A, Little A M, Marsh S G, Madrigal J A

Abstract excerpt

We describe the application of RSCA, for the high resolution typing of alleles encoded at the HLA-DPB1 locus. RSCA differs from other sequence based typing methodologies in that the HLA type is assigned on the basis of differences in DNA conformation between different alleles. A total of 251 samples were typed in a blind study, of these 109 samples had been typed previously by conventional techniques. A...

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PMID: 9796742
DOI: 10.1016/s0198-8859(98)00079-2

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