Article
High resolution HLA class I typing by reference strand mediated conformation analysis (RSCA).
Tissue antigens - 1 Jul 1998
Argüello J R, Little A M, Bohan E, Goldman J M, Marsh S G, Madrigal J A
Abstract excerpt
We describe the application of RSCA for the high resolution typing of alleles encoded within the highly polymorphic HLA class I system. RSCA differs from other sequence based typing methodologies in that the HLA type is assigned on the basis of differences in DNA conformation between different HL...
Topics
- Alleles
- Histocompatibility Antigens Class I
- Histocompatibility Testing
- Humans
- Polymerase Chain Reaction
- Polymorphism, Genetic