Construction of attenuated HIV-1 accessory gene immunization cassettes.

doi:10.1016/s0264-410x(98)00172-8

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Construction of attenuated HIV-1 accessory gene immunization cassettes.

Vaccine - 1 Nov 1998

Ayyavoo V, Nagashunmugam T, Phung M T, Buckner C, Kudckodkar S, Le P, Reddy P J, Santiago L, Patel M, Tea L, Weiner D B

Abstract excerpt

Delivery of genetic expression cassettes into animals can effectively induce both humoral and cellular immunity to the expressed gene product. Previously, we used this strategy to immunize against HIV-1 structural and enzymatic proteins in mice, non-human primates and in humans. In contrast, the...

Topics

AIDS Vaccines
Animals
Cell Line
Cytokines
Genes, Regulator
Genes, Viral
Genes, nef
Genes, vif
Genes, vpu
Genetic Variation
HIV-1
Humans
Lymphocyte Activation
Mice
Mutagenesis, Insertional
T-Lymphocytes, Cytotoxic
Vaccines, Attenuated
Vaccines, DNA

Source

Open in PubMed

Identifiers

PMID: 9795395
DOI: 10.1016/s0264-410x(98)00172-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9795395-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics