Article
Nicotinamide-adenine dinucleotide phosphate oxidase assembly and activation in EBV-transformed B lymphoblastoid cell lines of normal and chronic granulomatous disease patients.
Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 1998
Dusi S, Nadalini K A, Donini M, Zentilin L, Wientjes F B, Roos D, Giacca M, Rossi F
Abstract excerpt
This paper deals with the mechanisms of activation of NADPH oxidase investigated using EBV-transformed human B lymphoblastoid cell lines (B cells) from normal subjects and from patients affected by X-linked chronic granulomatous disease (CGD). The results reported are as follows. 1) In normal B c...
Topics
- B-Lymphocytes
- Biological Transport
- Cell Line, Transformed
- Cell Membrane
- Cytochrome b Group
- Enzyme Activation
- Granulomatous Disease, Chronic
- Herpesvirus 4, Human
- Humans
- Macromolecular Substances
- Male
- Membrane Glycoproteins
- Membrane Transport Proteins