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Article

African buffalo maintain high genetic diversity in the major histocompatibility complex in spite of historically known population bottlenecks.

Molecular ecology - 1 Oct 1998

Wenink P W, Groen A F, Roelke-Parker M E, Prins H H

Abstract excerpt

Historical population collapses caused by rinderpest epidemics are hypothesized to have resulted in notable genetic losses in populations of the African buffalo. Polymorphism in the major histocompatibity complex (MHC) DRB3 gene was probed by means of restriction analysis of the sequence encoding the peptide-binding region. Nucleotide substitution patterns agreed with a positive selection acting on this...

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PMID: 9787443
DOI: 10.1046/j.1365-294x.1998.00463.x

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