Article
Autophagy promotes caspase-dependent cell death during Drosophila development.
Autophagy - 1 Apr 2009
Mohseni Nilufar, McMillan Stephanie C, Chaudhary Roopali, Mok Jane, Reed Bruce H
Abstract excerpt
The relationship between autophagic cell death and apoptosis is a poorly understood aspect of programmed cell death (PCD). We have examined this relationship by studying the elimination of an extra-embryonic tissue, known as the amnioserosa (AS), during Drosophila development. The AS becomes autophagic during the final stages of embryogenesis; ultimately, however, the elimination of the AS involves...
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