Article
Beyond coagulation: fibrinogen as a cause of cardiovascular surgical disease.
Cardiovascular drugs and therapy - 1 Jul 1998
Sumeray M S, Montgomery H E, Humphries S E
Abstract excerpt
Fibrinogen is generally considered to be an important mediator of clot formation. However, its effects on clots and perhaps other more direct effects may also make it a powerful mediator in the genesis and progression of atheromatous disease. Indeed, raised fibrinogen levels may pose as great a cardiovascular risk as classical risk factors such as elevated blood pressure or cholesterol levels. The plasma...
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