Article
Differential validity of informant-based diagnoses of dementia and depression in index subjects and in their first-degree relatives.
Social psychiatry and psychiatric epidemiology - 1 Oct 1998
Heun R, Müller H, Papassotiropoulos A
Abstract excerpt
There is no study indicating that informant-derived information on dementia and depression (i.e. family history information) is equivalently valid for first-degree relatives and for index subjects (i.e. patients and control subjects). However, this unproven assumption is the basis for the frequent, possibly inappropriate, use of instruments validated for patients and control subjects in family studies which focus...
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